Homo sapiens Gene: LIPH
Summary
InnateDB Gene IDBG-68529.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LIPH
Gene Name lipase, member H
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000163898
Encoded Proteins
lipase, member H
lipase, member H
lipase, member H
lipase, member H
lipase, member H
Protein Structure
Entrez Gene
Summary This gene encodes a membrane-bound member of the mammalian triglyceride lipase family. It catalyzes the production of 2-acyl lysophosphatidic acid (LPA), which is a lipid mediator with diverse biological properties that include platelet aggregation, smooth muscle contraction, and stimulation of cell proliferation and motility. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:185506262-185552613
Strand Reverse strand
Band q27.2
Transcripts
ENST00000296252 ENSP00000296252
ENST00000424591 ENSP00000396384
ENST00000435679 ENSP00000390228
ENST00000452897 ENSP00000408218
ENST00000429510 ENSP00000414311
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004620 phospholipase activity
GO:0008201 heparin binding
GO:0016787 hydrolase activity
GO:0052689 carboxylic ester hydrolase activity
Biological Process
GO:0006629 lipid metabolic process
GO:0016042 lipid catabolic process
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q8WWY8
TrEMBL A2IBA6 A2IBA8 F8WE09
UniProt Splice Variant
Entrez Gene 200879
UniGene Hs.351126 Hs.68864
RefSeq NM_139248 XM_006713530
HUGO HGNC:18483
OMIM 607365
CCDS CCDS3272
HPRD 07392
IMGT
EMBL AC099661 AK074229 AK122651 AY036912 AY093498 BC064941 CH471052 EF186228 EF186229 EF186230
GenPept AAH64941 AAK63178 AAM18803 ABM67094 ABM67095 ABM67096 BAB85023 BAG53642 EAW78218
ImmGen LIPH (murine)
RNA Seq Atlas 200879