Version 5.4
Homo sapiens Gene: STYX
Summary
InnateDB Gene IDBG-6868.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STYX
Gene Name serine/threonine/tyrosine interacting protein
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000198252
Encoded Proteins
IDBP-6870
serine/threonine/tyrosine interacting protein
IDBP-369063
serine/threonine/tyrosine interacting protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a pseudophosphatase, able to bind potential substrates but lacking an active catalytic loop. The encoded protein may be involved in spermiogenesis. Two transcript variants encoding the same protein have been found for these genes. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:52730180-52774998
Strand Forward strand
Band q22.1
Transcripts
ENST00000354586 ENSP00000346599
ENST00000442123 ENSP00000403214
ENST00000556861
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008138 protein tyrosine/serine/threonine phosphatase activity
GO:0016791 phosphatase activity
Biological Process
GO:0006470 protein dephosphorylation
GO:0007283 spermatogenesis
GO:0016311 dephosphorylation
GO:0045204 MAPK export from nucleus
GO:0070372 regulation of ERK1 and ERK2 cascade
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q8WUJ0
TrEMBL A0A024R641
UniProt Splice Variant
Entrez Gene 6815
UniGene Hs.364980 Hs.596832 Hs.599935 Hs.601213
RefSeq NM_001130701 NM_145251 XM_006720242
HUGO HGNC:11447
OMIM 615814
CCDS CCDS9711
HPRD 10258
IMGT
EMBL AK098195 BC020265 BC146995 BC146998 CH471061 CH471078 U87169
GenPept AAB47561 AAH20265 AAI46996 AAI46999 BAC05259 EAW65641 EAW65644 EAW80612 EAW80613
RNA Seq Atlas 6815

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca