Version 5.4
Homo sapiens Gene: FETUB
Summary
InnateDB Gene IDBG-68968.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FETUB
Gene Name fetuin B
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000090512
Encoded Proteins
IDBP-68970
fetuin B
IDBP-68974
fetuin B
IDBP-68976
fetuin B
IDBP-386398
fetuin B
IDBP-386399
fetuin B
IDBP-386401
fetuin B
IDBP-386402
fetuin B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the fetuin family, part of the cystatin superfamily of cysteine protease inhibitors. Fetuins have been implicated in several diverse functions, including osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors, and response to systemic inflammation. This protein may be secreted by cells. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:186635969-186653141
Strand Forward strand
Band q27.3
Transcripts
ENST00000265029 ENSP00000265029
ENST00000382136 ENSP00000371571
ENST00000382134 ENSP00000371569
ENST00000450521 ENSP00000404288
ENST00000431018 ENSP00000396581
ENST00000435961 ENSP00000393851
ENST00000420570 ENSP00000405438
ENST00000488561
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0004869 cysteine-type endopeptidase inhibitor activity
GO:0008191 metalloendopeptidase inhibitor activity
Biological Process
GO:0007338 single fertilization
GO:0007339 binding of sperm to zona pellucida
GO:0008150 biological_process
GO:0010951 negative regulation of endopeptidase activity
Cellular Component
GO:0005615 extracellular space
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022871
View Gene Order
ENSBTAG00000017531
Not yet available
Cross-References
SwissProt
TrEMBL F8WEP7
UniProt Splice Variant
Entrez Gene 26998
UniGene Hs.81073
RefSeq XM_005247351 NM_014375
HUGO HGNC:3658
OMIM 605954
CCDS CCDS3279
HPRD 09335
IMGT
EMBL AC068631
GenPept
RNA Seq Atlas 26998

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca