Homo sapiens Gene: XAGE3
Summary
InnateDB Gene IDBG-69224.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol XAGE3
Gene Name X antigen family, member 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000171402
Encoded Proteins
X antigen family, member 3
X antigen family, member 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is expressed in placenta and fetal liver/spleen, and may function in inhibiting cancer cell growth. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene generates 2 transcript variants differing in the 5' UTR. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:52862525-52868068
Strand Reverse strand
Band p11.22
Transcripts
ENST00000375491 ENSP00000364640
ENST00000346279 ENSP00000303061
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_130776 NM_133179
HUGO
OMIM
CCDS CCDS14347
HPRD 06676
IMGT
EMBL
GenPept
RNA Seq Atlas