Version 5.4
Homo sapiens Gene: SMC5
Summary
InnateDB Gene IDBG-69731.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SMC5
Gene Name structural maintenance of chromosomes 5
Synonyms SMC5L1
Species Homo sapiens
Ensembl Gene ENSG00000198887
Encoded Proteins
IDBP-69735
structural maintenance of chromosomes 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 9:70258962-70354888
Strand Forward strand
Band q21.12
Transcripts
ENST00000361138 ENSP00000354957
ENST00000475540
ENST00000471372
ENST00000618375
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated
Total 17 [view]
Protein-Protein 17 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
Biological Process
GO:0000722 telomere maintenance via recombination
GO:0000724 double-strand break repair via homologous recombination
GO:0007067 mitotic nuclear division
GO:0034184 positive regulation of maintenance of mitotic sister chromatid cohesion
GO:0045842 positive regulation of mitotic metaphase/anaphase transition
GO:0090398 cellular senescence
Cellular Component
GO:0000781 chromosome, telomeric region
GO:0005634 nucleus
GO:0016605 PML body
GO:0030054 cell junction
GO:0030915 Smc5-Smc6 complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000024943
View Gene Order
ENSBTAG00000018437
Not yet available
Cross-References
SwissProt Q8IY18
TrEMBL
UniProt Splice Variant
Entrez Gene 23137
UniGene Hs.534189 Hs.711704
RefSeq NM_015110
HUGO HGNC:20465
OMIM 609386
CCDS CCDS6632
HPRD
IMGT
EMBL AB011166 AJ310550 AL162390 BC017666 BC038225
GenPept AAH17666 AAH38225 BAA25520 CAC39247 CAH73243
RNA Seq Atlas 23137

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca