Version 5.4
Homo sapiens Gene: IMP4
Summary
InnateDB Gene IDBG-69750.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IMP4
Gene Name IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000136718
Encoded Proteins
IDBP-69752
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
IDBP-294275
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
IDBP-294274
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
IDBP-385925
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
IDBP-385926
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
IDBP-385927
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary IMP4 forms a ternary complex with IMP3 (MIM 612980) and MPP10 (MPHOSPHO10; MIM 605503) that interacts with U3 small nucleolar RNA (snoRNA), which is required for the early cleavage steps in pre-rRNA processing (Granneman et al., 2003 [PubMed 12655004]).[supplied by OMIM, Aug 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:130342225-130347810
Strand Forward strand
Band q21.1
Transcripts
ENST00000259239 ENSP00000259239
ENST00000409935 ENSP00000386411
ENST00000409649 ENSP00000386716
ENST00000456713 ENSP00000416756
ENST00000428740 ENSP00000389701
ENST00000452955 ENSP00000409371
ENST00000462392
ENST00000464432
ENST00000490895
ENST00000473689
ENST00000470672
ENST00000477375
ENST00000495606
ENST00000460766
ENST00000460100
ENST00000462357
ENST00000475074
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006364 rRNA processing
Cellular Component
GO:0005730 nucleolus
GO:0030529 ribonucleoprotein complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026127
View Gene Order
ENSBTAG00000003225
Not yet available
Cross-References
SwissProt
TrEMBL F8WCN0
UniProt Splice Variant
Entrez Gene 92856
UniGene Hs.618071 Hs.91579
RefSeq NM_033416 XM_005263844
HUGO HGNC:30856
OMIM 612981
CCDS CCDS2160
HPRD 10002
IMGT
EMBL AC132479
GenPept
RNA Seq Atlas 92856

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca