Version 5.4
Homo sapiens Gene: TRPM3
Summary
InnateDB Gene IDBG-69916.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRPM3
Gene Name transient receptor potential cation channel, subfamily M, member 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000083067
Encoded Proteins
IDBP-69918
transient receptor potential cation channel, subfamily M, member 3
IDBP-69920
transient receptor potential cation channel, subfamily M, member 3
IDBP-69924
transient receptor potential cation channel, subfamily M, member 3
IDBP-69926
transient receptor potential cation channel, subfamily M, member 3
IDBP-69928
transient receptor potential cation channel, subfamily M, member 3
IDBP-69930
transient receptor potential cation channel, subfamily M, member 3
IDBP-69932
transient receptor potential cation channel, subfamily M, member 3
IDBP-69934
transient receptor potential cation channel, subfamily M, member 3
IDBP-69936
transient receptor potential cation channel, subfamily M, member 3
IDBP-237784
transient receptor potential cation channel, subfamily M, member 3
IDBP-237786
transient receptor potential cation channel, subfamily M, member 3
IDBP-237788
transient receptor potential cation channel, subfamily M, member 3
IDBP-237790
transient receptor potential cation channel, subfamily M, member 3
IDBP-293728
transient receptor potential cation channel, subfamily M, member 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The product of this gene belongs to the family of transient receptor potential (TRP) channels. TRP channels are cation-selective channels important for cellular calcium signaling and homeostasis. The protein encoded by this gene mediates calcium entry, and this entry is potentiated by calcium store depletion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:70529063-71446904
Strand Reverse strand
Band q21.13
Transcripts
ENST00000377111 ENSP00000366315
ENST00000377110 ENSP00000366314
ENST00000360823 ENSP00000354066
ENST00000377105 ENSP00000366309
ENST00000357533 ENSP00000350140
ENST00000358082 ENSP00000350791
ENST00000377101 ENSP00000366305
ENST00000361823 ENSP00000355395
ENST00000377097 ENSP00000366301
ENST00000354500
ENST00000396292 ENSP00000379587
ENST00000396285 ENSP00000379581
ENST00000396283 ENSP00000379579
ENST00000396280 ENSP00000379576
ENST00000408909 ENSP00000386127
ENST00000437699
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 1 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005261 cation channel activity
GO:0005262 calcium channel activity
Biological Process
GO:0006811 ion transport
GO:0006812 cation transport
GO:0034220 ion transmembrane transport
GO:0055085 transmembrane transport
GO:0070588 calcium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000052387
View Gene Order
ENSBTAG00000007778
Not yet available
Pathways
NETPATH
REACTOME
REACT_160189
Stimuli-sensing channels pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_25300
Ion channel transport pathway
REACT_169333
TRP channels pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.47288
RefSeq NM_001007470 NM_001007471 NM_020952 NM_024971 NM_206944 NM_206945 NM_206946 NM_206947 NM_206948 XM_005252218
HUGO
OMIM
CCDS CCDS43835 CCDS65064 CCDS6634 CCDS6635 CCDS6636 CCDS6637
HPRD 10605
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca