InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: FDX1

Summary

InnateDB Gene

IDBG-70670.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FDX1

Gene Name

ferredoxin 1

Synonyms

ADX; FDX; LOH11CR1D

Species

Homo sapiens

Ensembl Gene

ENSG00000137714

Encoded Proteins

IDBP-70672

ferredoxin 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene encodes a small iron-sulfur protein that transfers electrons from NADPH through ferredoxin reductase to mitochondrial cytochrome P450, involved in steroid, vitamin D, and bile acid metabolism. Pseudogenes of this functional gene are found on chromosomes 20 and 21. [provided by RefSeq, Aug 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 11:110429883-110464881

Strand

Forward strand

Band

q22.3

Transcripts

ENST00000260270

ENSP00000260270

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.

Experimentally validated
Total	7 [view]
Protein-Protein	5 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005506	iron ion binding
GO:0009055	electron carrier activity
GO:0051536	iron-sulfur cluster binding
GO:0051537	2 iron, 2 sulfur cluster binding

Biological Process

GO:0006694	steroid biosynthetic process
GO:0008203	cholesterol metabolic process
GO:0042446	hormone biosynthetic process
GO:0044281	small molecule metabolic process
GO:0055114	oxidation-reduction process