Homo sapiens Gene: HSPB2
Summary
InnateDB Gene IDBG-71095.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HSPB2
Gene Name Heat shock protein beta-2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000170276
Encoded Proteins
heat shock 27kDa protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The protein is expressed preferentially in the heart and skeletal muscle. This protein regulates Myotonic Dystrophy Protein Kinase, which plays an important role in maintenance of muscle structure and function. [provided by RefSeq, Dec 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:111912242-111914093
Strand Forward strand
Band q23.1
Transcripts
ENST00000304298 ENSP00000302476
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 30 experimentally validated interaction(s) in this database.
Experimentally validated
Total 30 [view]
Protein-Protein 30 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008047 enzyme activator activity
Biological Process
GO:0006986 response to unfolded protein
GO:0043085 positive regulation of catalytic activity
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
IL1 pathway
Leptin pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt Q16082
TrEMBL A8KAH6
UniProt Splice Variant
Entrez Gene 3316
UniGene Hs.709660
RefSeq NM_001541
HUGO HGNC:5247
OMIM 602179
CCDS CCDS8352
HPRD
IMGT
EMBL AK293041 AY208910 BC109393 CH471065 CR457408 D89617 EF444955 EF444984 S67070 U75898
GenPept AAB28816 AAB82757 AAI09394 AAO18081 ACA05948 ACA06000 BAA24004 BAF85730 CAG33689 EAW67168 EAW67169
RNA Seq Atlas 3316