Version 5.4
Homo sapiens Gene: PCYT1A
Summary
InnateDB Gene IDBG-71098.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PCYT1A
Gene Name phosphate cytidylyltransferase 1, choline, alpha
Synonyms CCTA; CT; CTA; CTPCT; PCYT1; SMDCRD
Species Homo sapiens
Ensembl Gene ENSG00000161217
Encoded Proteins
IDBP-71100
phosphate cytidylyltransferase 1, choline, alpha
IDBP-387048
phosphate cytidylyltransferase 1, choline, alpha
IDBP-387052
phosphate cytidylyltransferase 1, choline, alpha
IDBP-387053
phosphate cytidylyltransferase 1, choline, alpha
IDBP-387054
phosphate cytidylyltransferase 1, choline, alpha
IDBP-387055
phosphate cytidylyltransferase 1, choline, alpha
IDBP-387056
phosphate cytidylyltransferase 1, choline, alpha
IDBP-387058
phosphate cytidylyltransferase 1, choline, alpha
IDBP-387059
phosphate cytidylyltransferase 1, choline, alpha
IDBP-387060
phosphate cytidylyltransferase 1, choline, alpha
IDBP-387061
phosphate cytidylyltransferase 1, choline, alpha
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:196214222-196287957
Strand Reverse strand
Band q29
Transcripts
ENST00000292823 ENSP00000292823
ENST00000441879 ENSP00000392397
ENST00000419333 ENSP00000390968
ENST00000431016 ENSP00000394617
ENST00000411591 ENSP00000400430
ENST00000433733 ENSP00000390458
ENST00000430755 ENSP00000402283
ENST00000444822 ENSP00000397888
ENST00000412869 ENSP00000402015
ENST00000438634 ENSP00000391405
ENST00000443555 ENSP00000393341
ENST00000460827
ENST00000473978
ENST00000488235
ENST00000460677
ENST00000491544
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 7 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004105 choline-phosphate cytidylyltransferase activity
GO:0005515 protein binding
GO:0008289 lipid binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0006644 phospholipid metabolic process
GO:0006656 phosphatidylcholine biosynthetic process
GO:0006657 CDP-choline pathway
GO:0009058 biosynthetic process
GO:0044281 small molecule metabolic process
GO:0046474 glycerophospholipid biosynthetic process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0042587 glycogen granule
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000005615
View Gene Order
ENSBTAG00000016979
Not yet available
Pathways
NETPATH
REACTOME
REACT_121238
Synthesis of PC pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_121401
Glycerophospholipid biosynthesis pathway
REACT_120870
Phospholipid metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa00564
Glycerophospholipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.135997 Hs.732465 Hs.732774
RefSeq NM_005017
HUGO
OMIM
CCDS CCDS3315
HPRD 00438
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca