Homo sapiens Gene: SAMD4A
Summary
InnateDB Gene IDBG-7120.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SAMD4A
Gene Name sterile alpha motif domain containing 4A
Synonyms SAMD4; SMAUG; SMAUG1; SMG; SMGA
Species Homo sapiens
Ensembl Gene ENSG00000020577
Encoded Proteins
sterile alpha motif domain containing 4A
sterile alpha motif domain containing 4A
sterile alpha motif domain containing 4A
sterile alpha motif domain containing 4A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Sterile alpha motifs (SAMs) in proteins such as SAMD4A are part of an RNA-binding domain that functions as a posttranscriptional regulator by binding to an RNA sequence motif known as the Smaug recognition element, which was named after the Drosophila Smaug protein (Baez and Boccaccio, 2005 [PubMed 16221671]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:54567097-54793315
Strand Forward strand
Band q22.2
Transcripts
ENST00000251091 ENSP00000251091
ENST00000392067 ENSP00000375919
ENST00000554335 ENSP00000452535
ENST00000555112
ENST00000555091
ENST00000557692
ENST00000557013
ENST00000554587
ENST00000555192 ENSP00000450808
ENST00000556069
ENST00000553988
ENST00000555719
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0030371 translation repressor activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0017148 negative regulation of translation
GO:0045727 positive regulation of translation
Cellular Component
GO:0005737 cytoplasm
GO:0030054 cell junction
GO:0030425 dendrite
GO:0045202 synapse
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.602611 Hs.706976 Hs.733324 Hs.98259
RefSeq NM_001161576 NM_001161577 NM_015589
HUGO
OMIM
CCDS CCDS32084 CCDS55917 CCDS55918
HPRD 10209
IMGT
EMBL
GenPept
RNA Seq Atlas