Version 5.4
Homo sapiens Gene: GNL3L
Summary
InnateDB Gene IDBG-71375.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GNL3L
Gene Name guanine nucleotide binding protein-like 3 (nucleolar)-like
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000130119
Encoded Proteins
IDBP-71377
guanine nucleotide binding protein-like 3 (nucleolar)-like
IDBP-71379
guanine nucleotide binding protein-like 3 (nucleolar)-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene appears to be a nucleolar GTPase that is essential for ribosomal pre-rRNA processing and cell proliferation. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:54530211-54561071
Strand Forward strand
Band p11.22
Transcripts
ENST00000336470 ENSP00000338573
ENST00000360845 ENSP00000354091
ENST00000489691
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0015093 ferrous iron transmembrane transporter activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006184 GTP catabolic process
GO:0015684 ferrous iron transport
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000025266
View Gene Order
ENSBTAG00000031564
Not yet available
Cross-References
SwissProt Q9NVN8
TrEMBL A0A024R9Y6
UniProt Splice Variant
Entrez Gene 54552
UniGene Hs.654677
RefSeq NM_019067 NM_001184819
HUGO HGNC:25553
OMIM 300873
CCDS CCDS14360
HPRD 06514
IMGT
EMBL AK001475 AL391139 BC011720 CH471154
GenPept AAH11720 BAA91712 CAI40396 EAW93182 EAW93183 EAW93185
RNA Seq Atlas 54552

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca