Version 5.4
Homo sapiens Gene: RIF1
Summary
InnateDB Gene IDBG-72137.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RIF1
Gene Name RAP1 interacting factor homolog (yeast)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000080345
Encoded Proteins
IDBP-72139
RAP1 interacting factor homolog (yeast)
IDBP-386475
RAP1 interacting factor homolog (yeast)
IDBP-386477
RAP1 interacting factor homolog (yeast)
IDBP-386478
RAP1 interacting factor homolog (yeast)
IDBP-386483
RAP1 interacting factor homolog (yeast)
IDBP-386484
RAP1 interacting factor homolog (yeast)
IDBP-386485
RAP1 interacting factor homolog (yeast)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein that shares homology with the yeast teleomere binding protein, Rap1 interacting factor 1. This protein localizes to aberrant telomeres may be involved in DNA repair. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:151409883-151508013
Strand Forward strand
Band q23.3
Transcripts
ENST00000243326 ENSP00000243326
ENST00000453091 ENSP00000414615
ENST00000444746 ENSP00000390181
ENST00000428287 ENSP00000415691
ENST00000414861 ENSP00000390486
ENST00000430328 ENSP00000416123
ENST00000454583 ENSP00000404882
ENST00000457745
ENST00000494333
ENST00000498041
ENST00000484077
ENST00000467762
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 37 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 37 [view]
Protein-Protein 36 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
Biological Process
GO:0006974 cellular response to DNA damage stimulus
GO:0007049 cell cycle
GO:0019827 stem cell maintenance
Cellular Component
GO:0000781 chromosome, telomeric region
GO:0001939 female pronucleus
GO:0001940 male pronucleus
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005819 spindle
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036202
View Gene Order
ENSBTAG00000021020
Not yet available
Cross-References
SwissProt Q5UIP0
TrEMBL B4DRJ4 C9J1D6
UniProt Splice Variant
Entrez Gene 55183
UniGene Hs.601837 Hs.607851 Hs.655671 Hs.725354 Hs.725538 Hs.725631 Hs.735592
RefSeq NM_018151 NM_001177663 NM_001177664 NM_001177665 XM_005246665 XM_006712610 XM_006712611
HUGO HGNC:23207
OMIM 608952
CCDS CCDS2194 CCDS54406
HPRD 10603
IMGT
EMBL AC009311 AC009497 AK001461 AK022932 AK024033 AK074349 AK299291 AL080129 AY584066 AY585745 AY727910 AY727911 AY727912 AY727913 CR933663 U79263
GenPept AAB50209 AAS94233 AAT40745 AAV51401 AAV51402 AAV51403 AAV51404 BAA91705 BAB14313 BAB14792 BAB85058 BAG61306 CAB45727 CAI45961
RNA Seq Atlas 101929336 55183

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca