InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: THY1

Summary

InnateDB Gene

IDBG-74502.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

THY1

Gene Name

Thy-1 cell surface antigen

Synonyms

CD90

Species

Homo sapiens

Ensembl Gene

ENSG00000154096

Encoded Proteins

IDBP-74506

Thy-1 cell surface antigen

IDBP-594982

Thy-1 cell surface antigen

IDBP-589486

Thy-1 cell surface antigen

IDBP-592147

Thy-1 cell surface antigen

IDBP-583366

Thy-1 cell surface antigen

IDBP-719226

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 11:119417378-119424985

Strand

Reverse strand

Band

q23.3

Transcripts

ENST00000284240	ENSP00000284240
ENST00000528522	ENSP00000431301
ENST00000528295	ENSP00000432051
ENST00000527590
ENST00000524970	ENSP00000432808
ENST00000524659	ENSP00000435753
ENST00000532974
ENST00000533840
ENST00000580275	ENSP00000464248
ENST00000584021

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	24 [view]
Protein-Protein	24 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005100	Rho GTPase activator activity
GO:0005178	integrin binding
GO:0005515	protein binding
GO:0019899	enzyme binding
GO:0019901	protein kinase binding
GO:0034235	GPI anchor binding

Biological Process

GO:0001525	angiogenesis
GO:0006469	negative regulation of protein kinase activity
GO:0007010	cytoskeleton organization
GO:0016337	single organismal cell-cell adhesion
GO:0030336	negative regulation of cell migration
GO:0032321	positive regulation of Rho GTPase activity
GO:0043547	positive regulation of GTPase activity
GO:0046549	retinal cone cell development
GO:0048041	focal adhesion assembly
GO:0050771	negative regulation of axonogenesis
GO:0050852	T cell receptor signaling pathway
GO:0050860	negative regulation of T cell receptor signaling pathway
GO:0050870	positive regulation of T cell activation
GO:0051281	positive regulation of release of sequestered calcium ion into cytosol

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0009897	external side of plasma membrane
GO:0009986	cell surface
GO:0016324	apical plasma membrane
GO:0030425	dendrite
GO:0030426	growth cone
GO:0031362	anchored component of external side of plasma membrane
GO:0045121	membrane raft
GO:0046658	anchored component of plasma membrane
GO:0070062	extracellular vesicular exosome

Orthologs

Species

Mus musculus

Bos taurus

Gene ID

Gene Order

ENSMUSG00000032011

View Gene Order

ENSBTAG00000019627

Not yet available

Pathways

NETPATH

REACTOME

KEGG

hsa04670

Leukocyte transendothelial migration pathway

INOH

PID NCI

integrin2_pathway

Beta2 integrin cell surface interactions

il4_2pathway

IL4-mediated signaling events

integrin3_pathway

Beta3 integrin cell surface interactions

amb2_neutrophils_pathway

amb2 Integrin signaling

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Hs.743230

RefSeq

NM_006288

HUGO

OMIM

CCDS

CCDS8424

HPRD

11283

IMGT

EMBL

GenPept

RNA Seq Atlas