Version 5.4
Homo sapiens Gene: PLA2G4F
Summary
InnateDB Gene IDBG-7529.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLA2G4F
Gene Name phospholipase A2, group IVF
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000168907
Encoded Proteins
IDBP-7533
phospholipase A2, group IVF
IDBP-235726
phospholipase A2, group IVF
IDBP-747758
IDBP-747865
IDBP-746500
IDBP-746624
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 15:42139034-42156636
Strand Reverse strand
Band q15.1
Transcripts
ENST00000290497 ENSP00000290497
ENST00000397272 ENSP00000380442
ENST00000569985 ENSP00000454330
ENST00000565553 ENSP00000455513
ENST00000562320 ENSP00000455037
ENST00000561893
ENST00000561627 ENSP00000456697
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004620 phospholipase activity
GO:0004622 lysophospholipase activity
GO:0004623 phospholipase A2 activity
GO:0005515 protein binding
GO:0046872 metal ion binding
GO:0047498 calcium-dependent phospholipase A2 activity
Biological Process
GO:0001516 prostaglandin biosynthetic process
GO:0006644 phospholipid metabolic process
GO:0008152 metabolic process
GO:0009395 phospholipid catabolic process
GO:0015908 fatty acid transport
GO:0036148 phosphatidylglycerol acyl-chain remodeling
GO:0036149 phosphatidylinositol acyl-chain remodeling
GO:0036150 phosphatidylserine acyl-chain remodeling
GO:0036151 phosphatidylcholine acyl-chain remodeling
GO:0036152 phosphatidylethanolamine acyl-chain remodeling
GO:0044281 small molecule metabolic process
GO:0046474 glycerophospholipid biosynthetic process
GO:0050482 arachidonic acid secretion
GO:0071236 cellular response to antibiotic
GO:0071407 cellular response to organic cyclic compound
Cellular Component
GO:0005737 cytoplasm
GO:0005765 lysosomal membrane
GO:0005829 cytosol
GO:0031982 vesicle
GO:0032587 ruffle membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000046971
View Gene Order
ENSBTAG00000032068
Not yet available
Pathways
NETPATH
REACTOME
REACT_120829
Acyl chain remodelling of PC pathway
REACT_120722
Acyl chain remodelling of PI pathway
REACT_120977
Hydrolysis of LPC pathway
REACT_121384
Acyl chain remodelling of PS pathway
REACT_121324
Acyl chain remodelling of PG pathway
REACT_121369
Acyl chain remodelling of PE pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_121401
Glycerophospholipid biosynthesis pathway
REACT_120870
Phospholipid metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa00592
alpha-Linolenic acid metabolism pathway
hsa04912
GnRH signaling pathway pathway
hsa00590
Arachidonic acid metabolism pathway
hsa04370
VEGF signaling pathway pathway
hsa04664
Fc epsilon RI signaling pathway pathway
hsa04010
MAPK signaling pathway pathway
hsa00564
Glycerophospholipid metabolism pathway
hsa00591
Linoleic acid metabolism pathway
hsa04730
Long-term depression pathway
hsa00565
Ether lipid metabolism pathway
hsa04666
Fc gamma R-mediated phagocytosis pathway
hsa04270
Vascular smooth muscle contraction pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_213600
HUGO
OMIM
CCDS CCDS32204
HPRD 17326
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca