Version 5.4
Homo sapiens Gene: GDAP1L1
Summary
InnateDB Gene IDBG-76361.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GDAP1L1
Gene Name ganglioside induced differentiation associated protein 1-like 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000124194
Encoded Proteins
IDBP-76363
ganglioside-induced differentiation-associated protein 1-like 1
IDBP-76367
ganglioside-induced differentiation-associated protein 1-like 1
IDBP-375897
ganglioside-induced differentiation-associated protein 1-like 1
IDBP-375900
ganglioside-induced differentiation-associated protein 1-like 1
IDBP-375901
ganglioside-induced differentiation-associated protein 1-like 1
IDBP-588987
ganglioside-induced differentiation-associated protein 1-like 1
IDBP-810895
ganglioside induced differentiation associated protein 1-like 1
IDBP-810896
ganglioside induced differentiation associated protein 1-like 1
IDBP-810911
ganglioside induced differentiation associated protein 1-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein termed ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene was found in humans, and mutations in the human gene are associated with Charcot-Marie-Tooth type 4A disease. The protein encoded by this gene is similar in sequence to the human GDAP1 protein. Several transcript variants encoding different isoforms, as well as a noncoding transcript variant, have been found for this gene. [provided by RefSeq, Feb 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:44247099-44280917
Strand Forward strand
Band q13.12
Transcripts
ENST00000342560 ENSP00000341782
ENST00000372952 ENSP00000362043
ENST00000438466 ENSP00000392881
ENST00000445952 ENSP00000404128
ENST00000447658 ENSP00000391714
ENST00000537864 ENSP00000440498
ENST00000612599 ENSP00000480502
ENST00000617075 ENSP00000478701
ENST00000616372 ENSP00000483113
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000017943
View Gene Order
ENSBTAG00000002593
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 78997
UniGene
RefSeq NM_001256740 NM_001256737 NM_001256738 NM_001256739 NM_024034
HUGO HGNC:4213
OMIM
CCDS CCDS74726 CCDS13328 CCDS74725 CCDS74727
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas 78997

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca