Version 5.4
Homo sapiens Gene: PPP1R10
Summary
InnateDB Gene IDBG-76372.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPP1R10
Gene Name protein phosphatase 1, regulatory subunit 10
Synonyms CAT53; FB19; p99; PNUTS; PP1R10; R111
Species Homo sapiens
Ensembl Gene ENSG00000204569
Encoded Proteins
IDBP-76376
protein phosphatase 1, regulatory subunit 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein phosphatase 1 binding protein. The encoded protein plays a role in many cellular processes including cell cycle progression, DNA repair and apoptosis by regulating the activity of protein phosphatase 1. This gene lies within the major histocompatibility complex class I region on chromosome 6, and alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:30600400-30618612
Strand Reverse strand
Band p21.33
Transcripts
ENST00000376511 ENSP00000365694
ENST00000496955
ENST00000476704
ENST00000461593
ENST00000468181
ENST00000484449
ENST00000473954
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 39 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 39 [view]
Protein-Protein 38 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0004864 protein phosphatase inhibitor activity
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006606 protein import into nucleus
GO:0043086 negative regulation of catalytic activity
Cellular Component
GO:0000785 chromatin
GO:0005634 nucleus
GO:0072357 PTW/PP1 phosphatase complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000039220
View Gene Order
ENSBTAG00000006933
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.106019
RefSeq NM_002714 XM_006715130 XM_006715131 XM_006715132 XM_006725489 XM_006725703 XM_006725820 XM_006725912 XM_006725913 XM_006725914 XM_006726005 XM_006726100
HUGO
OMIM
CCDS CCDS4681
HPRD 04797
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca