Version 5.4
Homo sapiens Gene: SLC39A10
Summary
InnateDB Gene IDBG-77719.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC39A10
Gene Name solute carrier family 39 (zinc transporter), member 10
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000196950
Encoded Proteins
IDBP-77721
solute carrier family 39 (zinc transporter), member 10
IDBP-293269
solute carrier family 39 (zinc transporter), member 10
IDBP-388109
solute carrier family 39 (zinc transporter), member 10
IDBP-388110
solute carrier family 39 (zinc transporter), member 10
IDBP-388111
solute carrier family 39 (zinc transporter), member 10
IDBP-388113
solute carrier family 39 (zinc transporter), member 10
IDBP-388115
solute carrier family 39 (zinc transporter), member 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A10 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:195575977-195737702
Strand Forward strand
Band q32.3
Transcripts
ENST00000359634 ENSP00000352655
ENST00000409086 ENSP00000386766
ENST00000458054 ENSP00000389640
ENST00000444421 ENSP00000394469
ENST00000430412 ENSP00000394995
ENST00000412905 ENSP00000406590
ENST00000418005 ENSP00000409272
ENST00000464301
ENST00000465851
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0046873 metal ion transmembrane transporter activity
Biological Process
GO:0006829 zinc ion transport
GO:0030001 metal ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000025986
View Gene Order
ENSBTAG00000016782
Not yet available
Pathways
NETPATH
REACTOME
REACT_20603
Zinc influx into cells by the SLC39 gene family pathway
REACT_20547
Metal ion SLC transporters pathway
REACT_19305
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_20530
Zinc transporters pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.650158
RefSeq NM_001127257 NM_020342 XM_005246689 XM_005246692
HUGO
OMIM
CCDS CCDS33353
HPRD 10572
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca