Version 5.4
Homo sapiens Gene: DNAH7
Summary
InnateDB Gene IDBG-77740.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DNAH7
Gene Name dynein, axonemal, heavy chain 7
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000118997
Encoded Proteins
IDBP-77742
dynein, axonemal, heavy chain 7
IDBP-293264
dynein, axonemal, heavy chain 7
IDBP-293261
dynein, axonemal, heavy chain 7
IDBP-388118
dynein, axonemal, heavy chain 7
IDBP-388119
dynein, axonemal, heavy chain 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary DNAH7 is a component of the inner dynein arm of ciliary axonemes (Zhang et al., 2002 [PubMed 11877439]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:195737703-196068812
Strand Reverse strand
Band q32.3
Transcripts
ENST00000312428 ENSP00000311273
ENST00000409063 ENSP00000386912
ENST00000410072 ENSP00000386260
ENST00000438565 ENSP00000409732
ENST00000427816 ENSP00000407444
ENST00000484183
ENST00000493844
ENST00000475293
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003777 microtubule motor activity
GO:0005509 calcium ion binding
GO:0005524 ATP binding
GO:0008312 7S RNA binding
GO:0016887 ATPase activity
Biological Process
GO:0001539 cilium or flagellum-dependent cell motility
GO:0003341 cilium movement
GO:0006200 ATP catabolic process
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0007018 microtubule-based movement
GO:0008152 metabolic process
Cellular Component
GO:0005858 axonemal dynein complex
GO:0005874 microtubule
GO:0005929 cilium
GO:0030286 dynein complex
GO:0048500 signal recognition particle
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
hsa05016
Huntington's disease pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.97403
RefSeq NM_018897
HUGO
OMIM
CCDS CCDS42794
HPRD 10914
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca