Version 5.4
Homo sapiens Gene: HECW2
Summary
InnateDB Gene IDBG-77770.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HECW2
Gene Name HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000138411
Encoded Proteins
IDBP-77772
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
IDBP-293257
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
IDBP-388129
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
IDBP-388130
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:196194370-196593692
Strand Reverse strand
Band q32.3
Transcripts
ENST00000260983 ENSP00000260983
ENST00000409111 ENSP00000386775
ENST00000452031 ENSP00000409918
ENST00000427457 ENSP00000395770
ENST00000498146
ENST00000462290
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 286 experimentally validated interaction(s) in this database.
Experimentally validated
Total 286 [view]
Protein-Protein 286 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0016874 ligase activity
Biological Process
GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000042807
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.612353 Hs.654742
RefSeq NM_020760 XM_006712646 XM_006712648 XM_006712649
HUGO
OMIM
CCDS CCDS33354
HPRD 17099
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca