InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: PPP3CB

Summary

InnateDB Gene

IDBG-78455.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PPP3CB

Gene Name

protein phosphatase 3, catalytic subunit, beta isozyme

Synonyms

CALNA2; CALNB; CNA2; PP2Bbeta

Species

Homo sapiens

Ensembl Gene

ENSG00000107758

Encoded Proteins

IDBP-78457

protein phosphatase 3, catalytic subunit, beta isozyme

IDBP-78459

protein phosphatase 3, catalytic subunit, beta isozyme

IDBP-240783

protein phosphatase 3, catalytic subunit, beta isozyme

IDBP-240785

protein phosphatase 3, catalytic subunit, beta isozyme

IDBP-379840

protein phosphatase 3, catalytic subunit, beta isozyme

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 10:73436428-73496024

Strand

Reverse strand

Band

q22.2

Transcripts

ENST00000360663	ENSP00000353881
ENST00000342558	ENSP00000343147
ENST00000394829	ENSP00000378306
ENST00000394828	ENSP00000378305
ENST00000430762	ENSP00000398022
ENST00000495897

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	29 [view]
Protein-Protein	28 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004721	phosphoprotein phosphatase activity
GO:0004722	protein serine/threonine phosphatase activity
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0005516	calmodulin binding
GO:0008144	drug binding
GO:0016787	hydrolase activity
GO:0019899	enzyme binding
GO:0030346	protein phosphatase 2B binding
GO:0033192	calmodulin-dependent protein phosphatase activity
GO:0046983	protein dimerization activity

Biological Process

GO:0001915	negative regulation of T cell mediated cytotoxicity
GO:0006468	protein phosphorylation
GO:0006470	protein dephosphorylation
GO:0007165	signal transduction
GO:0007507	heart development
GO:0007612	learning
GO:0007613	memory
GO:0010468	regulation of gene expression
GO:0016311	dephosphorylation
GO:0017156	calcium ion-dependent exocytosis
GO:0030217	T cell differentiation
GO:0031987	locomotion involved in locomotory behavior
GO:0034097	response to cytokine
GO:0035176	social behavior
GO:0035690	cellular response to drug
GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0038095	Fc-epsilon receptor signaling pathway
GO:0042098	T cell proliferation
GO:0042110	T cell activation
GO:0043029	T cell homeostasis
GO:0045087	innate immune response
GO:0045893	positive regulation of transcription, DNA-templated
GO:0048167	regulation of synaptic plasticity
GO:0048675	axon extension
GO:0050796	regulation of insulin secretion