Version 5.4
Homo sapiens Gene: MPP4
Summary
InnateDB Gene IDBG-78725.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MPP4
Gene Name membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000082126
Encoded Proteins
IDBP-78727
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
IDBP-78729
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
IDBP-236537
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
IDBP-293161
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
IDBP-293159
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
IDBP-293160
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
IDBP-388382
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
IDBP-388384
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
IDBP-812424
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
IDBP-812425
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) protein family, with an N-terminal PDZ domain, a central src homology 3 region (SH3), and a C-terminal guanylate kinase-like (GUK) domain. The protein is localized to the outer limiting membrane in the retina, and is thought to function in photoreceptor polarity and the organization of specialized intercellular junctions. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:201644870-201698694
Strand Reverse strand
Band q33.1
Transcripts
ENST00000315506 ENSP00000319363
ENST00000359962 ENSP00000353047
ENST00000396886 ENSP00000380095
ENST00000409474 ENSP00000387278
ENST00000409143 ENSP00000387293
ENST00000409818 ENSP00000386580
ENST00000428900 ENSP00000416781
ENST00000447335 ENSP00000406160
ENST00000486212
ENST00000483841
ENST00000602867 ENSP00000473500
ENST00000620095 ENSP00000478875
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0035418 protein localization to synapse
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0042734 presynaptic membrane
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000079550
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.63085
RefSeq NM_033066 XM_005246732 XM_005246734 XM_005246735 XM_005246736
HUGO
OMIM
CCDS CCDS46491
HPRD 07360
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca