Version 5.4
Homo sapiens Gene: CYP20A1
Summary
InnateDB Gene IDBG-79059.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CYP20A1
Gene Name cytochrome P450, family 20, subfamily A, polypeptide 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000119004
Encoded Proteins
IDBP-79061
cytochrome P450, family 20, subfamily A, polypeptide 1
IDBP-388451
cytochrome P450, family 20, subfamily A, polypeptide 1
IDBP-388452
cytochrome P450, family 20, subfamily A, polypeptide 1
IDBP-388454
cytochrome P450, family 20, subfamily A, polypeptide 1
IDBP-388456
cytochrome P450, family 20, subfamily A, polypeptide 1
IDBP-388457
cytochrome P450, family 20, subfamily A, polypeptide 1
IDBP-807361
cytochrome P450, family 20, subfamily A, polypeptide 1
IDBP-807365
cytochrome P450, family 20, subfamily A, polypeptide 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein lacks one amino acid of the conserved heme binding site. It also lacks the conserved I-helix motif AGX(D,E)T, suggesting that its substrate may carry its own oxygen. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:203238449-203305840
Strand Forward strand
Band q33.2
Transcripts
ENST00000356079 ENSP00000348380
ENST00000429815 ENSP00000407860
ENST00000449301 ENSP00000414831
ENST00000428265 ENSP00000398046
ENST00000431118 ENSP00000388070
ENST00000443941 ENSP00000411341
ENST00000461371
ENST00000463131
ENST00000489360
ENST00000611416 ENSP00000477866
ENST00000613925 ENSP00000482757
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding
Biological Process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000049439
View Gene Order
ENSBTAG00000000851
Not yet available
Cross-References
SwissProt
TrEMBL F8WBE2
UniProt Splice Variant
Entrez Gene 57404
UniGene Hs.446065
RefSeq XM_005246701 NM_177538 XM_005246698 XM_006712644 XM_006712645
HUGO HGNC:20576
OMIM
CCDS CCDS2357
HPRD 07100
IMGT
EMBL AC011737 AC080075
GenPept
RNA Seq Atlas 57404

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca