Version 5.4
Homo sapiens Gene: AAMP
Summary
InnateDB Gene IDBG-80875.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AAMP
Gene Name angio-associated, migratory cell protein
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000127837
Encoded Proteins
IDBP-80877
angio-associated, migratory cell protein
IDBP-388873
angio-associated, migratory cell protein
IDBP-388874
angio-associated, migratory cell protein
IDBP-388876
angio-associated, migratory cell protein
IDBP-388877
angio-associated, migratory cell protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 19535145
AAMP over-expression inhibits NOD1 and NOD2 mediated NF-kappaB signalling
Entrez Gene
Summary The gene product is an immunoglobulin-type protein. It is found to be expressed strongly in endothelial cells, cytotrophoblasts, and poorly differentiated colon adenocarcinoma cells found in lymphatics. The protein contains a heparin-binding domain and mediates heparin-sensitive cell adhesion. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:218264123-218270257
Strand Reverse strand
Band q35
Transcripts
ENST00000248450 ENSP00000248450
ENST00000444053 ENSP00000403343
ENST00000420660 ENSP00000416394
ENST00000422731 ENSP00000396295
ENST00000447885 ENSP00000393818
ENST00000475678
ENST00000494720
ENST00000489767
ENST00000465442
ENST00000461911
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
Experimentally validated
Total 26 [view]
Protein-Protein 24 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008201 heparin binding
Biological Process
GO:0001525 angiogenesis
GO:0010595 positive regulation of endothelial cell migration
GO:0014909 smooth muscle cell migration
GO:0030154 cell differentiation
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0009986 cell surface
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000006299
View Gene Order
ENSBTAG00000003927
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.612676 Hs.83347
RefSeq NM_001087 XM_005246325
HUGO
OMIM
CCDS CCDS33378
HPRD 04600
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca