Version 5.4
Homo sapiens Gene: SNCG
Summary
InnateDB Gene IDBG-81145.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SNCG
Gene Name synuclein, gamma (breast cancer-specific protein 1)
Synonyms BCSG1; SR
Species Homo sapiens
Ensembl Gene ENSG00000173267
Encoded Proteins
IDBP-81147
synuclein, gamma (breast cancer-specific protein 1)
IDBP-81149
synuclein, gamma (breast cancer-specific protein 1)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. Mutations in this gene have also been associated with breast tumor development. [provided by RefSeq, Jan 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:86958618-86963260
Strand Forward strand
Band q23.2
Transcripts
ENST00000348795 ENSP00000344658
ENST00000372017 ENSP00000361087
ENST00000465679
ENST00000483064
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
Experimentally validated
Total 29 [view]
Protein-Protein 29 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0043014 alpha-tubulin binding
GO:0048487 beta-tubulin binding
Biological Process
GO:0002118 aggressive behavior
GO:0007268 synaptic transmission
GO:0008344 adult locomotory behavior
GO:0009306 protein secretion
GO:0014059 regulation of dopamine secretion
GO:0042220 response to cocaine
GO:0042493 response to drug
GO:0046928 regulation of neurotransmitter secretion
GO:0050808 synapse organization
GO:0071464 cellular response to hydrostatic pressure
Cellular Component
GO:0005737 cytoplasm
GO:0005815 microtubule organizing center
GO:0005819 spindle
GO:0005886 plasma membrane
GO:0030424 axon
GO:0043025 neuronal cell body
GO:0043679 axon terminus
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000023064
View Gene Order
ENSBTAG00000003515
Not yet available
Cross-References
SwissProt O76070
TrEMBL F8W754 Q6FHG5
UniProt Splice Variant
Entrez Gene 6623
UniGene
RefSeq NM_003087 XM_005270065 XM_005270066 XM_005270067
HUGO HGNC:11141
OMIM 602998
CCDS CCDS7380
HPRD
IMGT
EMBL AC025268 AF010126 AF017256 AF037207 AF044311 AF411524 AK223367 AK312141 BC014098 CH471142 CR541788 CR541790
GenPept AAB64109 AAC27738 AAC36550 AAC36586 AAH14098 AAL05870 BAD97087 BAG35077 CAG46587 CAG46589 EAW80316 EAW80317
RNA Seq Atlas 6623

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca