Version 5.4
Homo sapiens Gene: RNLS
Summary
InnateDB Gene IDBG-81462.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RNLS
Gene Name renalase, FAD-dependent amine oxidase
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000184719
Encoded Proteins
IDBP-81464
renalase, FAD-dependent amine oxidase
IDBP-81466
renalase, FAD-dependent amine oxidase
IDBP-381933
renalase, FAD-dependent amine oxidase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Renalase is a flavin adenine dinucleotide-dependent amine oxidase that is secreted into the blood from the kidney (Xu et al., 2005 [PubMed 15841207]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:88273864-88584530
Strand Reverse strand
Band q23.31
Transcripts
ENST00000371947 ENSP00000361015
ENST00000331772 ENSP00000332530
ENST00000437752 ENSP00000387577
ENST00000466945
ENST00000481793
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 1 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016491 oxidoreductase activity
Biological Process
GO:0002931 response to ischemia
GO:0003073 regulation of systemic arterial blood pressure
GO:0003214 cardiac left ventricle morphogenesis
GO:0042414 epinephrine metabolic process
GO:0042415 norepinephrine metabolic process
GO:0042417 dopamine metabolic process
GO:0055062 phosphate ion homeostasis
GO:0055114 oxidation-reduction process
GO:0060047 heart contraction
GO:0071869 response to catecholamine
GO:0071871 response to epinephrine
GO:0071873 response to norepinephrine
GO:1902074 response to salt
Cellular Component
GO:0005615 extracellular space
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000071573
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.149849
RefSeq NM_001031709 NM_018363
HUGO
OMIM
CCDS CCDS31239 CCDS7388
HPRD 07742
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca