Version 5.4
Homo sapiens Gene: SP140
Summary
InnateDB Gene IDBG-82911.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SP140
Gene Name SP140 nuclear body protein
Synonyms LYSP100; LYSP100-A; LYSP100-B
Species Homo sapiens
Ensembl Gene ENSG00000079263
Encoded Proteins
IDBP-82917
SP140 nuclear body protein
IDBP-82919
SP140 nuclear body protein
IDBP-246459
SP140 nuclear body protein
IDBP-389215
SP140 nuclear body protein
IDBP-389216
SP140 nuclear body protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:230203110-230313215
Strand Forward strand
Band q37.1
Transcripts
ENST00000343805 ENSP00000342096
ENST00000373645 ENSP00000362749
ENST00000392045 ENSP00000375899
ENST00000420434 ENSP00000398210
ENST00000417495 ENSP00000393618
ENST00000473711
ENST00000476126
ENST00000486750
ENST00000479539
ENST00000543928
ENST00000544128
ENST00000538494
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006952 defense response
Cellular Component
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL E9PFJ6
UniProt Splice Variant
Entrez Gene 11262
UniGene Hs.632549
RefSeq NM_001278452 NM_001005176 NM_001278451 NM_001278453 NM_007237 XM_005246252 XM_006712223 XM_006712224
HUGO HGNC:17133
OMIM 608602
CCDS CCDS63151 CCDS33392 CCDS42831 CCDS63149 CCDS63150
HPRD 09780
IMGT
EMBL AC009949 AC009950
GenPept
RNA Seq Atlas 101928789 11262

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca