Homo sapiens Gene: AKAP14
Summary
InnateDB Gene IDBG-84127.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AKAP14
Gene Name A kinase (PRKA) anchor protein 14
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000186471
Encoded Proteins
A kinase (PRKA) anchor protein 14
A kinase (PRKA) anchor protein 14
A kinase (PRKA) anchor protein 14
A kinase (PRKA) anchor protein 14
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The protein anchors PKA in ciliary axonemes and, in this way, may play a role in regulating ciliary beat frequency. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:119895837-119920716
Strand Forward strand
Band q24
Transcripts
ENST00000371431 ENSP00000360485
ENST00000371425 ENSP00000360479
ENST00000334356 ENSP00000334680
ENST00000371422 ENSP00000360476
ENST00000491105
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0051018 protein kinase A binding
Biological Process
GO:0007283 spermatogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0035686 sperm fibrous sheath
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q86UN6
TrEMBL
UniProt Splice Variant
Entrez Gene 158798
UniGene Hs.592245
RefSeq NM_178813 NM_001008534 NM_001008535
HUGO HGNC:24061
OMIM 300462
CCDS CCDS14591 CCDS35376 CCDS35377
HPRD 02353
IMGT
EMBL AF514780 AF514781 AF514782 BC066357
GenPept AAH66357 AAP20825 AAP20826 AAP20827
RNA Seq Atlas 158798