Version 5.4
Homo sapiens Gene: SLC26A8
Summary
InnateDB Gene IDBG-84563.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC26A8
Gene Name solute carrier family 26, member 8
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000112053
Encoded Proteins
IDBP-84565
solute carrier family 26, member 8
IDBP-241238
solute carrier family 26, member 8
IDBP-475031
solute carrier family 26, member 8
IDBP-474907
solute carrier family 26, member 8
IDBP-477563
solute carrier family 26, member 8
IDBP-479162
solute carrier family 26, member 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the SLC26 gene family of anion transporters. Family members are well conserved in gene structure and protein length yet have markedly different tissue expression patterns. The expression of this gene appears to be restricted to spermatocytes. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:35943514-36024868
Strand Reverse strand
Band p21.31
Transcripts
ENST00000355574 ENSP00000347778
ENST00000394602 ENSP00000378100
ENST00000490799 ENSP00000417638
ENST00000466805
ENST00000465492 ENSP00000418107
ENST00000486155
ENST00000469847 ENSP00000419700
ENST00000480663 ENSP00000420488
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005254 chloride channel activity
GO:0005515 protein binding
GO:0015116 sulfate transmembrane transporter activity
GO:0015301 anion:anion antiporter activity
GO:0019531 oxalate transmembrane transporter activity
Biological Process
GO:0006820 anion transport
GO:0006821 chloride transport
GO:0007126 meiotic nuclear division
GO:0007275 multicellular organismal development
GO:0007283 spermatogenesis
GO:0008272 sulfate transport
GO:0019532 oxalate transport
GO:0030154 cell differentiation
GO:1902358 sulfate transmembrane transport
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036196
View Gene Order
ENSBTAG00000017251
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.435836
RefSeq NM_001193476 NM_052961 NM_138718 XM_006714996
HUGO
OMIM
CCDS CCDS4813 CCDS4814
HPRD 12241
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca