Version 5.4
Homo sapiens Gene: MMP23B
Summary
InnateDB Gene IDBG-85653.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MMP23B
Gene Name matrix metallopeptidase 23B
Synonyms MIFR; MIFR-1; MMP22; MMP23A
Species Homo sapiens
Ensembl Gene ENSG00000189409
Encoded Proteins
IDBP-85655
matrix metallopeptidase 23B
IDBP-85659
matrix metallopeptidase 23B
IDBP-361999
matrix metallopeptidase 23B
IDBP-482075
matrix metallopeptidase 23B
IDBP-477586
matrix metallopeptidase 23B
IDBP-473849
matrix metallopeptidase 23B
IDBP-474532
matrix metallopeptidase 23B
IDBP-722379
IDBP-813365
matrix metallopeptidase 23B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene (MMP23B) encodes a member of the matrix metalloproteinase (MMP) family, and it is part of a duplicated region of chromosome 1p36.3. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. This gene belongs to the more telomeric copy of the duplicated region. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:1632095-1701810
Strand Forward strand
Band p36.33
Transcripts
ENST00000356026 ENSP00000348308
ENST00000378675 ENSP00000367945
ENST00000435358 ENSP00000405867
ENST00000472264 ENSP00000424976
ENST00000512731 ENSP00000423780
ENST00000479814 ENSP00000426293
ENST00000503792 ENSP00000426857
ENST00000489782
ENST00000486400
ENST00000490017 ENSP00000462142
ENST00000618459 ENSP00000482664
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0005515 protein binding
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0000003 reproduction
GO:0006508 proteolysis
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0005622 intracellular
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
GO:0031012 extracellular matrix
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029061
View Gene Order
ENSBTAG00000010732
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.671760
RefSeq NM_006983 XM_005244810 XM_006710993
HUGO
OMIM
CCDS CCDS30559
HPRD 04503
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca