Version 5.4
Homo sapiens Gene: MMEL1
Summary
InnateDB Gene IDBG-86465.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MMEL1
Gene Name membrane metallo-endopeptidase-like 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000142606
Encoded Proteins
IDBP-86467
membrane metallo-endopeptidase-like 1
IDBP-721617
IDBP-481490
membrane metallo-endopeptidase-like 1
IDBP-475153
membrane metallo-endopeptidase-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. This protein is a type II transmembrane protein and is thought to be expressed as a secreted protein. This gene is expressed mainly in testis with weak expression in the brain, kidney, and heart. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:2590639-2632990
Strand Reverse strand
Band p36.32
Transcripts
ENST00000378412 ENSP00000367668
ENST00000471840 ENSP00000461938
ENST00000502556 ENSP00000422492
ENST00000504800 ENSP00000425477
ENST00000464195
ENST00000491941
ENST00000469962
ENST00000509374
ENST00000511099
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005615 extracellular space
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000058183
View Gene Order
ENSBTAG00000009349
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.591453
RefSeq NM_033467
HUGO
OMIM
CCDS CCDS30569
HPRD 07024
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca