Version 5.4
| Homo sapiens Gene: TAF8 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-87010.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | TAF8 | ||||||||||||||||||
| Gene Name | TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa | ||||||||||||||||||
| Synonyms | |||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000137413 | ||||||||||||||||||
| Encoded Proteins |
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
This gene encodes one of several TATA-binding protein (TBP)-associated factors (TAFs), which are integral subunits of the general transcription factor complex TFIID. TFIID recognizes the core promoter of many genes and nucleates the assembly of a transcription preinitiation complex containing RNA polymerase II and other initiation factors. The protein encoded by this gene contains an H4-like histone fold domain, and interacts with several subunits of TFIID including TBP and the histone-fold protein TAF10. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 6:42050513-42087461 | ||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||
| Band | p21.1 | ||||||||||||||||||
| Transcripts | |||||||||||||||||||
| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 33 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME | |||||||||||||||||||
| KEGG |
Basal transcription factors pathway
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| INOH | |||||||||||||||||||
| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | Q7Z7C8 | ||||||||||||||||||
| TrEMBL | |||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 129685 | ||||||||||||||||||
| UniGene | Hs.520122 Hs.671858 Hs.694242 | ||||||||||||||||||
| RefSeq | NM_138572 XM_005248849 | ||||||||||||||||||
| HUGO | HGNC:17300 | ||||||||||||||||||
| OMIM | 100740 609514 | ||||||||||||||||||
| CCDS | CCDS43462 | ||||||||||||||||||
| HPRD | 18167 | ||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AF465841 AK057383 AL512274 AL513008 BC119678 BC119679 | ||||||||||||||||||
| GenPept | AAI19679 AAI19680 AAP47094 BAB71460 CAI15202 CAI15203 CAI16781 CAI16782 | ||||||||||||||||||
| RNA Seq Atlas | 129685 | ||||||||||||||||||