Homo sapiens Gene: POLL
Summary
InnateDB Gene IDBG-87156.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol POLL
Gene Name polymerase (DNA directed), lambda
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000166169
Encoded Proteins
polymerase (DNA directed), lambda
polymerase (DNA directed), lambda
polymerase (DNA directed), lambda
polymerase (DNA directed), lambda
polymerase (DNA directed), lambda
polymerase (DNA directed), lambda
polymerase (DNA directed), lambda
polymerase (DNA directed), lambda
polymerase (DNA directed), lambda
polymerase (DNA directed), lambda
polymerase (DNA directed), lambda
polymerase (DNA directed), lambda
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a DNA polymerase. DNA polymerases catalyze DNA-template-directed extension of the 3'-end of a DNA strand. This particular polymerase, which is a member of the X family of DNA polymerases, likely plays a role in non-homologous end joining and other DNA repair processes. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:101578882-101588270
Strand Reverse strand
Band q24.32
Transcripts
ENST00000370172 ENSP00000359191
ENST00000299206 ENSP00000299206
ENST00000339310 ENSP00000343102
ENST00000370169 ENSP00000359188
ENST00000370168 ENSP00000359187
ENST00000370162 ENSP00000359181
ENST00000415897 ENSP00000400676
ENST00000429502 ENSP00000406791
ENST00000426919 ENSP00000411678
ENST00000454524 ENSP00000390093
ENST00000413344 ENSP00000400517
ENST00000430045 ENSP00000414293
ENST00000463515
ENST00000485369
ENST00000470140
ENST00000461587
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
Experimentally validated
Total 16 [view]
Protein-Protein 14 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0003887 DNA-directed DNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0016829 lyase activity
GO:0034061 DNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-dependent DNA replication
GO:0006281 DNA repair
GO:0006289 nucleotide-excision repair
GO:0016446 somatic hypermutation of immunoglobulin genes
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Non-homologous end-joining pathway
Base excision repair pathway
INOH
PID NCI
DNA-PK pathway in nonhomologous end joining
Cross-References
SwissProt
TrEMBL Q5ZEY5 Q9HBN3
UniProt Splice Variant
Entrez Gene 27343
UniGene
RefSeq NM_001174084 NM_001174085 NM_013274 XM_006717770 XM_006717771 XM_006717777 XM_006717778 XM_006717779
HUGO HGNC:9184
OMIM 606343
CCDS CCDS7513
HPRD 09394
IMGT
EMBL AF218027 AJ844642 AL627424 CH471066
GenPept AAG17269 CAH59754 EAW49765
RNA Seq Atlas 27343