Version 5.4
Homo sapiens Gene: LIME1
Summary
InnateDB Gene IDBG-87257.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LIME1
Gene Name Lck interacting transmembrane adaptor 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000203896
Encoded Proteins
IDBP-87259
Lck interacting transmembrane adaptor 1
IDBP-381120
Lck interacting transmembrane adaptor 1
IDBP-810909
IDBP-808720
Lck interacting transmembrane adaptor 1
IDBP-808723
Lck interacting transmembrane adaptor 1
IDBP-808724
Lck interacting transmembrane adaptor 1
IDBP-808725
Lck interacting transmembrane adaptor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary LIME1 is a raft-associated transmembrane adaptor phosphoprotein that is preferentially expressed in hemopoietic cells, particularly T cells (Brdickova et al., 2003 [PubMed 14610046]; Hur et al., 2003 [PubMed 14610044]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:63736283-63739103
Strand Forward strand
Band q13.33
Transcripts
ENST00000309546 ENSP00000309521
ENST00000444951 ENSP00000414506
ENST00000496820 ENSP00000477596
ENST00000465591
ENST00000487026 ENSP00000482812
ENST00000480139 ENSP00000477561
ENST00000493265 ENSP00000476772
ENST00000476183 ENSP00000478705
ENST00000489212
ENST00000494776
ENST00000621325
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0050852 T cell receptor signaling pathway
GO:0050853 B cell receptor signaling pathway
Cellular Component
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000090077
View Gene Order
ENSBTAG00000007501
Not yet available
Pathways
NETPATH
NetPath_11
TCR pathway
NetPath_12
BCR pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_017806
HUGO
OMIM
CCDS CCDS13536
HPRD 07904
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca