Version 5.4
Homo sapiens Gene: ABCC10
Summary
InnateDB Gene IDBG-88083.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ABCC10
Gene Name ATP-binding cassette, sub-family C (CFTR/MRP), member 10
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000124574
Encoded Proteins
IDBP-88085
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
IDBP-88087
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
IDBP-88089
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
IDBP-477596
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:43427366-43450430
Strand Forward strand
Band p21.1
Transcripts
ENST00000372530 ENSP00000361608
ENST00000372515 ENSP00000361593
ENST00000244533 ENSP00000244533
ENST00000372512
ENST00000437104
ENST00000443426
ENST00000502549
ENST00000463024
ENST00000469856
ENST00000505344 ENSP00000422699
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0042626 ATPase activity, coupled to transmembrane movement of substances
Biological Process
GO:0006200 ATP catabolic process
GO:0006810 transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005765 lysosomal membrane
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000032842
View Gene Order
ENSBTAG00000005842
Not yet available
Pathways
NETPATH
REACTOME
REACT_15480
ABC-family proteins mediated transport pathway
REACT_15518
Transmembrane transport of small molecules pathway
KEGG
hsa02010
ABC transporters pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.55879 Hs.598395 Hs.737964 Hs.742827
RefSeq NM_001198934 NM_033450
HUGO
OMIM
CCDS CCDS4896 CCDS56430
HPRD 07623
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca