InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: NEURL

Summary

InnateDB Gene

IDBG-88573.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NEURL

Gene Name

neuralized homolog (Drosophila)

Synonyms

bA416N2.1; neu; neu-1; NEUR1; NEURL; RNF67

Species

Homo sapiens

Ensembl Gene

ENSG00000107954

Encoded Proteins

IDBP-88575

neuralized homolog (Drosophila)

IDBP-385088

neuralized homolog (Drosophila)

IDBP-385089

neuralized homolog (Drosophila)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 10:103493979-103592552

Strand

Forward strand

Band

q24.33

Transcripts

ENST00000369780	ENSP00000358795
ENST00000437579	ENSP00000416709
ENST00000455386	ENSP00000387714
ENST00000465048

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0016874	ligase activity
GO:0045183	translation factor activity, non-nucleic acid binding

Biological Process

GO:0006417	regulation of translation
GO:0006513	protein monoubiquitination
GO:0007219	Notch signaling pathway
GO:0007288	sperm axoneme assembly
GO:0007399	nervous system development
GO:0007595	lactation
GO:0008285	negative regulation of cell proliferation
GO:0030317	sperm motility
GO:0043065	positive regulation of apoptotic process
GO:0045741	positive regulation of epidermal growth factor-activated receptor activity
GO:0045746	negative regulation of Notch signaling pathway
GO:0048170	positive regulation of long-term neuronal synaptic plasticity
GO:0051491	positive regulation of filopodium assembly
GO:0060999	positive regulation of dendritic spine development
GO:0071230	cellular response to amino acid stimulus
GO:0090129	positive regulation of synapse maturation

Cellular Component

GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0014069	postsynaptic density
GO:0030054	cell junction
GO:0043197	dendritic spine
GO:0043204	perikaryon
GO:0045211	postsynaptic membrane
GO:0048471	perinuclear region of cytoplasm
GO:0097440	apical dendrite