Version 5.4
Homo sapiens Gene: NTMT1
Summary
InnateDB Gene IDBG-89167.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NTMT1
Gene Name N-terminal Xaa-Pro-Lys N-methyltransferase 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000148335
Encoded Proteins
IDBP-89169
methyltransferase like 11A
IDBP-89171
methyltransferase like 11A
IDBP-89173
methyltransferase like 11A
IDBP-89175
methyltransferase like 11A
IDBP-811895
N-terminal Xaa-Pro-Lys N-methyltransferase 1
IDBP-811898
N-terminal Xaa-Pro-Lys N-methyltransferase 1
IDBP-811899
N-terminal Xaa-Pro-Lys N-methyltransferase 1
IDBP-811903
N-terminal Xaa-Pro-Lys N-methyltransferase 1
IDBP-811904
N-terminal Xaa-Pro-Lys N-methyltransferase 1
IDBP-811905
N-terminal Xaa-Pro-Lys N-methyltransferase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The METTL11A gene encodes an N-terminal methyltransferase for the RAN (MIM 601179) guanine nucleotide exchange factor regulator of chromosome condensation 1 (RCC1; MIM 179710). METTL11A enzyme alpha-N-methylates other protein targets such as SET (MIM 600960) and RB (MIM 180200).[supplied by OMIM, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:129608884-129636131
Strand Forward strand
Band q34.11
Transcripts
ENST00000372486 ENSP00000361564
ENST00000372483 ENSP00000361561
ENST00000372481 ENSP00000361559
ENST00000372480 ENSP00000361558
ENST00000481189 ENSP00000473916
ENST00000459968 ENSP00000474445
ENST00000482347 ENSP00000473900
ENST00000486391
ENST00000617943 ENSP00000484447
ENST00000613644 ENSP00000478521
ENST00000611055 ENSP00000483489
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008168 methyltransferase activity
GO:0008171 O-methyltransferase activity
GO:0008276 protein methyltransferase activity
Biological Process
GO:0007051 spindle organization
GO:0007059 chromosome segregation
GO:0008152 metabolic process
GO:0018012 N-terminal peptidyl-alanine trimethylation
GO:0018016 N-terminal peptidyl-proline dimethylation
GO:0032259 methylation
GO:0035572 N-terminal peptidyl-serine dimethylation
GO:0035573 N-terminal peptidyl-serine trimethylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026857
View Gene Order
ENSBTAG00000015437
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001286796 NM_001286797 NM_001286798 NM_001286799 NM_001286800 NM_001286801 NM_001286802 NM_001286803 NM_014064
HUGO
OMIM
CCDS CCDS35160 CCDS69682 CCDS75918
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca