Version 5.4
Homo sapiens Gene: AGTRAP
Summary
InnateDB Gene IDBG-89584.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AGTRAP
Gene Name angiotensin II receptor-associated protein
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000177674
Encoded Proteins
IDBP-89586
angiotensin II receptor-associated protein
IDBP-89588
angiotensin II receptor-associated protein
IDBP-89590
angiotensin II receptor-associated protein
IDBP-89592
angiotensin II receptor-associated protein
IDBP-227140
angiotensin II receptor-associated protein
IDBP-368928
angiotensin II receptor-associated protein
IDBP-483528
angiotensin II receptor-associated protein
IDBP-474469
angiotensin II receptor-associated protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates angiotensin II signaling. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:11736084-11754802
Strand Forward strand
Band p36.22
Transcripts
ENST00000376637 ENSP00000365824
ENST00000376629 ENSP00000365816
ENST00000376627 ENSP00000365814
ENST00000314340 ENSP00000319713
ENST00000400895 ENSP00000383688
ENST00000452018 ENSP00000408505
ENST00000476512 ENSP00000424455
ENST00000494437
ENST00000491346
ENST00000510878 ENSP00000422647
ENST00000476309
ENST00000514733
ENST00000513739
ENST00000471765
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
Experimentally validated
Total 20 [view]
Protein-Protein 20 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004945 angiotensin type II receptor activity
GO:0005515 protein binding
Biological Process
GO:0001666 response to hypoxia
GO:0008217 regulation of blood pressure
GO:0038166 angiotensin-activated signaling pathway
Cellular Component
GO:0000139 Golgi membrane
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0005938 cell cortex
GO:0016021 integral component of membrane
GO:0030659 cytoplasmic vesicle membrane
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001040194 NM_001040195 NM_001040196 NM_001040197 NM_020350
HUGO
OMIM
CCDS CCDS136 CCDS30585 CCDS30586 CCDS41248 CCDS44056
HPRD 16379
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca