Homo sapiens Gene: OPN1MW2 | |||||||||||||
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Summary | |||||||||||||
InnateDB Gene | IDBG-90927.6 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | OPN1MW2 | ||||||||||||
Gene Name | opsin 1 (cone pigments), medium-wave-sensitive 2 | ||||||||||||
Synonyms | |||||||||||||
Species | Homo sapiens | ||||||||||||
Ensembl Gene | ENSG00000166160 | ||||||||||||
Encoded Proteins |
opsin 1 (cone pigments), medium-wave-sensitive 2
opsin 1 (cone pigments), medium-wave-sensitive 2
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Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
This gene encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called green cone photopigment or medium-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. The long-wavelength opsin gene and multiple copies of the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of deutanopic colorblindness. [provided by RefSeq, Mar 2009] |
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Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome X:154219756-154233286 | ||||||||||||
Strand | Forward strand | ||||||||||||
Band | q28 | ||||||||||||
Transcripts |
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Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||
No orthologs found for this gene | |||||||||||||
Pathways | |||||||||||||
NETPATH | |||||||||||||
REACTOME |
G alpha (i) signalling events pathway
Opsins pathway
Class A/1 (Rhodopsin-like receptors) pathway
The retinoid cycle in cones (daylight vision) pathway
Retinoid cycle disease events pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
Diseases associated with visual transduction pathway
Visual phototransduction pathway
GPCR ligand binding pathway
Disease pathway
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KEGG | |||||||||||||
INOH | |||||||||||||
PID NCI | |||||||||||||
Cross-References | |||||||||||||
SwissProt | P04001 | ||||||||||||
TrEMBL | |||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 728458 | ||||||||||||
UniGene | Hs.247787 Hs.571751 | ||||||||||||
RefSeq | NM_001048181 XM_003960089 XM_005276725 | ||||||||||||
HUGO | HGNC:26952 | ||||||||||||
OMIM | 300821 | ||||||||||||
CCDS | CCDS35447 | ||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
EMBL | AC092402 K03490 K03491 K03492 K03493 K03494 K03495 K03496 K03497 M13306 Z46936 | ||||||||||||
GenPept | AAB59503 AAB59525 | ||||||||||||
RNA Seq Atlas | 101060233 2652 728458 | ||||||||||||