Version 5.4
Homo sapiens Gene: CACUL1
Summary
InnateDB Gene IDBG-90944.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CACUL1
Gene Name CDK2-associated, cullin domain 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000151893
Encoded Proteins
IDBP-90948
chromosome 10 open reading frame 46
IDBP-603307
chromosome 10 open reading frame 46
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 10:118674167-118755249
Strand Reverse strand
Band q26.11
Transcripts
ENST00000369151 ENSP00000358147
ENST00000493518 ENSP00000431329
ENST00000490610
ENST00000489169
ENST00000481360
ENST00000477583
ENST00000544392
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019901 protein kinase binding
GO:0031625 ubiquitin protein ligase binding
Biological Process
GO:0000082 G1/S transition of mitotic cell cycle
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0008284 positive regulation of cell proliferation
GO:0045860 positive regulation of protein kinase activity
Cellular Component
GO:0031461 cullin-RING ubiquitin ligase complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000033417
View Gene Order
ENSBTAG00000022808
Not yet available
Cross-References
SwissProt Q86Y37
TrEMBL
UniProt Splice Variant
Entrez Gene 143384
UniGene Hs.743319
RefSeq NM_153810 XM_005269559
HUGO HGNC:23727
OMIM
CCDS CCDS41570
HPRD
IMGT
EMBL AJ544771 AK097728 AL139407 AY743663 BC038294
GenPept AAH38294 AAU89709 BAC05153 CAD67614 CAH73727
RNA Seq Atlas 143384

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca