InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: EIF3A

Summary

InnateDB Gene

IDBG-90993.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

EIF3A

Gene Name

eukaryotic translation initiation factor 3, subunit A

Synonyms

EIF3; eIF3-p170; eIF3-theta; EIF3S10; P167; p180; p185; TIF32

Species

Homo sapiens

Ensembl Gene

ENSG00000107581

Encoded Proteins

IDBP-90995

eukaryotic translation initiation factor 3, subunit A

IDBP-591618

eukaryotic translation initiation factor 3, subunit A

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 10:119033670-119080823

Strand

Reverse strand

Band

q26.11

Transcripts

ENST00000369144	ENSP00000358140
ENST00000462527
ENST00000541549	ENSP00000438178

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 139 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	139 [view]
Protein-Protein	138 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003743	translation initiation factor activity
GO:0005198	structural molecule activity
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0001731	formation of translation preinitiation complex
GO:0001732	formation of translation initiation complex
GO:0006412	translation
GO:0006413	translational initiation
GO:0006446	regulation of translational initiation
GO:0010467	gene expression
GO:0044267	cellular protein metabolic process

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005852	eukaryotic translation initiation factor 3 complex
GO:0016020	membrane
GO:0016282	eukaryotic 43S preinitiation complex
GO:0033290	eukaryotic 48S preinitiation complex
GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m