Version 5.4
Homo sapiens Gene: CNO
Summary
InnateDB Gene IDBG-9118.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CNO
Gene Name biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000186222
Encoded Proteins
IDBP-9122
cappuccino homolog (mouse)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This intronless gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and is a model for Hermansky-Pudlak syndrome. The encoded protein may play a role in intracellular vesicular trafficking. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:6716055-6717671
Strand Forward strand
Band p16.1
Transcripts
ENST00000320776 ENSP00000318128
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006892 post-Golgi vesicle-mediated transport
GO:0008089 anterograde axon cargo transport
GO:0031175 neuron projection development
GO:0032438 melanosome organization
GO:0048490 anterograde synaptic vesicle transport
GO:0050885 neuromuscular process controlling balance
GO:0061024 membrane organization
GO:0070527 platelet aggregation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0031083 BLOC-1 complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000060708
View Gene Order
ENSBTAG00000003766
Not yet available
Pathways
NETPATH
REACTOME
REACT_19400
Golgi Associated Vesicle Biogenesis pathway
REACT_19187
Clathrin derived vesicle budding pathway
REACT_11235
trans-Golgi Network Vesicle Budding pathway
REACT_11123
Membrane Trafficking pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.7570
RefSeq NM_018366
HUGO
OMIM
CCDS CCDS3393
HPRD 12035
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca