Version 5.4
Homo sapiens Gene: INPP5F
Summary
InnateDB Gene IDBG-91238.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol INPP5F
Gene Name inositol polyphosphate-5-phosphatase F
Synonyms hSAC2; MSTPO47; SAC2
Species Homo sapiens
Ensembl Gene ENSG00000198825
Encoded Proteins
IDBP-91244
inositol polyphosphate-5-phosphatase F
IDBP-91246
inositol polyphosphate-5-phosphatase F
IDBP-91248
inositol polyphosphate-5-phosphatase F
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase and contains a Sac domain. The activity of this protein is specific for phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:119726097-119829278
Strand Forward strand
Band q26.11
Transcripts
ENST00000361976 ENSP00000354519
ENST00000369081 ENSP00000358077
ENST00000369080 ENSP00000358076
ENST00000490818
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0042578 phosphoric ester hydrolase activity
Biological Process
GO:0008152 metabolic process
GO:0014898 cardiac muscle hypertrophy in response to stress
GO:0031161 phosphatidylinositol catabolic process
GO:0048015 phosphatidylinositol-mediated signaling
GO:0051896 regulation of protein kinase B signaling
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000042105
View Gene Order
ENSBTAG00000021801
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.369755 Hs.595031 Hs.708423
RefSeq NM_001243194 NM_014937
HUGO
OMIM
CCDS CCDS58098 CCDS7616
HPRD 11048
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca