Version 5.4
Homo sapiens Gene: SEC16A
Summary
InnateDB Gene IDBG-92412.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SEC16A
Gene Name SEC16 homolog A (S. cerevisiae)
Synonyms KIAA0310; p250; SEC16L
Species Homo sapiens
Ensembl Gene ENSG00000148396
Encoded Proteins
IDBP-92414
SEC16 homolog A (S. cerevisiae)
IDBP-92416
SEC16 homolog A (S. cerevisiae)
IDBP-92418
SEC16 homolog A (S. cerevisiae)
IDBP-92420
SEC16 homolog A (S. cerevisiae)
IDBP-92422
SEC16 homolog A (S. cerevisiae)
IDBP-384008
SEC16 homolog A (S. cerevisiae)
IDBP-384012
SEC16 homolog A (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein that forms part of the Sec16 complex. This protein has a role in protein transport from the endoplasmic reticulum (ER) to the Golgi and mediates COPII vesicle formation at the transitional ER. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Feb 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:136440096-136483759
Strand Reverse strand
Band q34.3
Transcripts
ENST00000313084 ENSP00000317437
ENST00000313050 ENSP00000325827
ENST00000290037 ENSP00000290037
ENST00000371706 ENSP00000360771
ENST00000277537 ENSP00000277537
ENST00000431893 ENSP00000387583
ENST00000453963 ENSP00000403525
ENST00000467838
ENST00000472305
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 41 experimentally validated interaction(s) in this database.
Experimentally validated
Total 41 [view]
Protein-Protein 41 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007029 endoplasmic reticulum organization
GO:0015031 protein transport
GO:0021762 substantia nigra development
GO:0048208 COPII vesicle coating
Cellular Component
GO:0000139 Golgi membrane
GO:0005737 cytoplasm
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026924
View Gene Order
ENSBTAG00000023933
Not yet available
Pathways
NETPATH
NetPath_9
TNFalpha pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.522500 Hs.602836
RefSeq NM_001276418 NM_014866 XM_005266132 XM_005266136
HUGO
OMIM
CCDS CCDS55351 CCDS75936
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca