Version 5.4
Homo sapiens Gene: RABL6
Summary
InnateDB Gene IDBG-92660.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RABL6
Gene Name RAB, member RAS oncogene family-like 6
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000196642
Encoded Proteins
IDBP-92680
chromosome 9 open reading frame 86
IDBP-92686
chromosome 9 open reading frame 86
IDBP-92688
chromosome 9 open reading frame 86
IDBP-92690
chromosome 9 open reading frame 86
IDBP-384169
chromosome 9 open reading frame 86
IDBP-384172
chromosome 9 open reading frame 86
IDBP-384173
chromosome 9 open reading frame 86
IDBP-384176
chromosome 9 open reading frame 86
IDBP-588367
chromosome 9 open reading frame 86
IDBP-601956
chromosome 9 open reading frame 86
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the Ras superfamily of small GTPases. The encoded protein binds to both GTP and GDP and may play a role in cell growth and survival. Overexpression of this gene may play a role in breast cancer tumorigenesis, and pseudogenes of this gene are located on the long arm of chromosome 2 and the short arm of chromosome 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:136807922-136957733
Strand Forward strand
Band q34.3
Transcripts
ENST00000311502 ENSP00000311134
ENST00000371671 ENSP00000360736
ENST00000357466 ENSP00000350056
ENST00000371663 ENSP00000360727
ENST00000432842 ENSP00000414081
ENST00000436380 ENSP00000412757
ENST00000425121 ENSP00000395490
ENST00000435930 ENSP00000408442
ENST00000471502
ENST00000484471 ENSP00000433031
ENST00000464941 ENSP00000431675
ENST00000466096
ENST00000461992
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
Experimentally validated
Total 22 [view]
Protein-Protein 22 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000015087
View Gene Order
ENSBTAG00000039573
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.370555 Hs.592337
RefSeq NM_001173988 NM_001173989 NM_024718
HUGO
OMIM
CCDS CCDS48058 CCDS55352 CCDS55353
HPRD 12984
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca