Homo sapiens Gene: PLA2G2E

Summary
InnateDB Gene IDBG-92781.4
Last Modified 2011-02-17   [Report errors or provide feedback]
Gene Symbol PLA2G2E
Gene Name phospholipase A2, group IIE
Synonyms GIIE sPLA2; sPLA2-IIE
Species Homo sapiens
Ensembl Gene ENSG00000188784
Encoded Proteins
IDBP-92783 phospholipase A2, group IIE
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1: 20246502-20250110
Strand Reverse strand
Band p36.13
Transcripts
ENST00000375116  ENSP00000364257
Interactions
Number of Interactions   This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
 
Gene Ontology
Accession GO Term
Molecular Function
GO:0004623 phospholipase A2 activity
GO:0005509 calcium ion binding
Biological Process
GO:0006644 phospholipid metabolic process
GO:0006654 phosphatidic acid biosynthetic process
GO:0006954 inflammatory response
GO:0016042 lipid catabolic process
GO:0036148 phosphatidylglycerol acyl-chain remodeling
GO:0036149 phosphatidylinositol acyl-chain remodeling
GO:0036150 phosphatidylserine acyl-chain remodeling
GO:0036151 phosphatidylcholine acyl-chain remodeling
GO:0036152 phosphatidylethanolamine acyl-chain remodeling
GO:0044281 small molecule metabolic process
GO:0046474 glycerophospholipid biosynthetic process
Cellular Component
GO:0005576 extracellular region
Orthologs
Species
Mus musculus
Bos taurus
Gene ID Gene Order Method Confidence Comments
ENSMUSG00000028751 Ortholuge SSD Ortholog Ortholog supports species divergence
ENSBTAG00000004418 Not yet available Ortholuge SSD Ortholog Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
hsa00592  Alpha-Linolenic acid metabolism
hsa00590  Arachidonic acid metabolism
hsa00565  Ether lipid metabolism
hsa04975  Fat digestion and absorption
hsa04664  Fc epsilon RI signaling pathway
hsa00564  Glycerophospholipid metabolism
hsa04912  GnRH signaling pathway
hsa00591  Linoleic acid metabolism
hsa04730  Long-term depression
hsa04010  MAPK signaling pathway
hsa01100  Metabolic pathways
hsa04972  Pancreatic secretion
hsa05145  Toxoplasmosis
hsa04370  VEGF signaling pathway
hsa04270  Vascular smooth muscle contraction
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q9NZK7 
TrEMBL
UniProt Splice Variant
Entrez Gene 30814 
UniGene Hs.272372
RefSeq NM_014589 
HUGO 13414 
OMIM
CCDS CCDS200 
HPRD 07143
IMGT
EMBL AF189279 AL358253
GenPept AAF36541  CAH74016 
ImmGen PLA2G2E (murine) 
RNA Seq Atlas 30814