Version 5.4
Homo sapiens Gene: LCN12
Summary
InnateDB Gene IDBG-92891.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LCN12
Gene Name lipocalin 12
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000184925
Encoded Proteins
IDBP-92895
lipocalin 12
IDBP-92897
lipocalin 12
IDBP-811599
lipocalin 12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Members of the lipocalin family, such as LCN12, have a common structure consisting of an 8-stranded antiparallel beta-barrel that forms a cup-shaped ligand-binding pocket or calyx. Lipocalins generally bind small hydrophobic ligands and transport them to specific cells (Suzuki et al., 2004 [PubMed 15363845]).[supplied by OMIM, Aug 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:136949551-136955497
Strand Forward strand
Band q34.3
Transcripts
ENST00000371633 ENSP00000360696
ENST00000371632 ENSP00000360695
ENST00000484304
ENST00000470501
ENST00000492820
ENST00000491316
ENST00000463714
ENST00000495410
ENST00000491603
ENST00000496895
ENST00000471615 ENSP00000473473
ENST00000494713
ENST00000476751
ENST00000466277
ENST00000480204
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0001972 retinoic acid binding
GO:0005215 transporter activity
Biological Process
GO:0006629 lipid metabolic process
GO:0006810 transport
Cellular Component
GO:0005576 extracellular region
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_23892
Transport of fatty acids pathway
REACT_22285
Transport of vitamins, nucleosides, and related molecules pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_267716
Orphan transporters pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q5SQ16
UniProt Splice Variant
Entrez Gene 286256
UniGene Hs.440519
RefSeq XM_005266070 NM_178536 XM_005266068 XM_006717065 XM_006717066
HUGO HGNC:28733
OMIM 612905
CCDS CCDS7018
HPRD 13978
IMGT
EMBL AL807752
GenPept
RNA Seq Atlas 286256

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca