Version 5.4
Homo sapiens Gene: NKX6-2
Summary
InnateDB Gene IDBG-93505.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NKX6-2
Gene Name NK6 homeobox 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000148826
Encoded Proteins
IDBP-93507
NK6 homeobox 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 10:132783179-132786052
Strand Reverse strand
Band q26.3
Transcripts
ENST00000368592 ENSP00000357581
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000976 transcription regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006355 regulation of transcription, DNA-templated
GO:0010454 negative regulation of cell fate commitment
GO:0010455 positive regulation of cell fate commitment
GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification
GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification
GO:0022010 central nervous system myelination
GO:0030154 cell differentiation
GO:0031018 endocrine pancreas development
GO:0045686 negative regulation of glial cell differentiation
GO:0045687 positive regulation of glial cell differentiation
GO:0048709 oligodendrocyte differentiation
GO:0050885 neuromuscular process controlling balance
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000041309
View Gene Order
Cross-References
SwissProt Q9C056
TrEMBL
UniProt Splice Variant
Entrez Gene 84504
UniGene Hs.134013
RefSeq NM_177400
HUGO HGNC:19321
OMIM 605955
CCDS CCDS7670
HPRD
IMGT
EMBL AF184215 AL392043 BC101635 BC104823 CH471211
GenPept AAI01636 AAI04824 AAK13251 CAI39943 EAW61308
RNA Seq Atlas 84504

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca