Version 5.4
Homo sapiens Gene: NUDC
Summary
InnateDB Gene IDBG-94765.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NUDC
Gene Name nuclear distribution C homolog (A. nidulans)
Synonyms HNUDC; MNUDC; NPD011
Species Homo sapiens
Ensembl Gene ENSG00000090273
Encoded Proteins
IDBP-94767
nuclear distribution gene C homolog (A. nidulans)
IDBP-376782
nuclear distribution gene C homolog (A. nidulans)
IDBP-376788
nuclear distribution gene C homolog (A. nidulans)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a nuclear distribution protein that plays an essential role in mitosis and cytokinesis. The encoded protein is involved in spindle formation during mitosis and in microtubule organization during cytokinesis. Pseudogenes of this gene are found on chromosome 2. [provided by RefSeq, Feb 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:26900238-26946862
Strand Forward strand
Band p36.11
Transcripts
ENST00000321265 ENSP00000319664
ENST00000435827 ENSP00000404020
ENST00000452707 ENSP00000400981
ENST00000484772
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 127 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 127 [view]
Protein-Protein 127 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0007067 mitotic nuclear division
GO:0007275 multicellular organismal development
GO:0008283 cell proliferation
Cellular Component
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005874 microtubule
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028851
View Gene Order
ENSBTAG00000004416
Not yet available
Pathways
NETPATH
REACTOME
REACT_150425
Resolution of Sister Chromatid Cohesion pathway
REACT_682
Mitotic Prometaphase pathway
REACT_150471
Separation of Sister Chromatids pathway
REACT_1932
Mitotic Telophase/Cytokinesis pathway
REACT_115566
Cell Cycle pathway
REACT_910
M Phase pathway
REACT_1275
Mitotic Anaphase pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_150314
Mitotic Metaphase and Anaphase pathway
KEGG
INOH
PID NCI
lis1pathway
Lissencephaly gene (LIS1) in neuronal migration and development
plk1_pathway
PLK1 signaling events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 10726
UniGene
RefSeq NM_006600
HUGO HGNC:8045
OMIM 610325
CCDS CCDS292
HPRD 10122
IMGT
EMBL
GenPept
RNA Seq Atlas 10726

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca