Version 5.4
Homo sapiens Gene: NDUFA6
Summary
InnateDB Gene IDBG-9680.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NDUFA6
Gene Name NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa
Synonyms B14; CI-B14; LYRM6; NADHB14
Species Homo sapiens
Ensembl Gene ENSG00000184983
Encoded Proteins
IDBP-475002
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa
IDBP-807304
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa
IDBP-807303
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa
IDBP-807307
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 22:42085525-42090955
Strand Reverse strand
Band q13.2
Transcripts
ENST00000498737 ENSP00000418842
ENST00000470753 ENSP00000473478
ENST00000602404 ENSP00000473461
ENST00000617763 ENSP00000482543
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 5 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008137 NADH dehydrogenase (ubiquinone) activity
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0006979 response to oxidative stress
GO:0022904 respiratory electron transport chain
GO:0044237 cellular metabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005747 mitochondrial respiratory chain complex I
GO:0031966 mitochondrial membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022450
View Gene Order
ENSBTAG00000009509
Not yet available
Pathways
NETPATH
REACTOME
REACT_22393
Respiratory electron transport pathway
REACT_6305
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
REACT_111083
The citric acid (TCA) cycle and respiratory electron transport pathway
REACT_111217
Metabolism pathway
KEGG
hsa05010
Alzheimer's disease pathway
hsa00190
Oxidative phosphorylation pathway
hsa05012
Parkinson's disease pathway
hsa05016
Huntington's disease pathway
INOH
PID NCI
Cross-References
SwissProt P56556
TrEMBL R4GN43
UniProt Splice Variant
Entrez Gene 4700
UniGene Hs.274416
RefSeq NM_002490
HUGO HGNC:7690
OMIM 602138
CCDS CCDS33656
HPRD
IMGT
EMBL AF047182 AK291874 AK316562 AL021878 BC002772 CH471095 CR456529 CR456714 CR541997
GenPept AAC04267 AAH02772 BAF84563 BAG38151 CAG30415 CAG32995 CAG46794 EAW60489
RNA Seq Atlas 4700

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca